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Inhibition of intracellular Histoplasma capsulatum replication by murine macrophages that produce human defensin.

Although purified defensins are effective microbicides in vitro, their operation within intact phagocytes has not been established. To address this question, we inserted cDNA encoding human defensin HNP-1 into a pBabe/neo retroviral vector and transduced it into RAW 264.7 cells, a murine macrophage...

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Detaylı Bibliyografya
Yayımlandı:Infect Immun
Asıl Yazarlar: Couto, M A, Liu, L, Lehrer, R I, Ganz, T
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 1994
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186521/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8188361/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.6.2375-2378.1994
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