Inhibition of intracellular Histoplasma capsulatum replication by murine macrophages that produce human defensin.

Although purified defensins are effective microbicides in vitro, their operation within intact phagocytes has not been established. To address this question, we inserted cDNA encoding human defensin HNP-1 into a pBabe/neo retroviral vector and transduced it into RAW 264.7 cells, a murine macrophage...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Couto, M A, Liu, L, Lehrer, R I, Ganz, T
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186521/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8188361/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.6.2375-2378.1994
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