An intracellular arrangement of Histoplasma capsulatum yeast-aggregates generates nuclear damage to the cultured murine alveolar macrophages

Histoplasma capsulatum is responsible for a human systemic mycosis that primarily affects lung tissue. Macrophages are the major effector cells in humans that respond to the fungus, and the development of respiratory disease depends on the ability of Histoplasma yeast cells to survive and replicate...

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Detalhes bibliográficos

Principais autores:	Nayla De Souza Pitangui, Janaina De Cássia Orlandi Sardi, Aline Raquel eVoltan, Claudia Tavares edos Santos, Julhiany De Fátima Da Silva, Rosângela Aparecida Moraes da Silva, Felipe Oliveira Souza, Christiane Pienna Soares, Gabriela eRodríguez-Arellanes, Maria Lúcia Taylor, Maria José Soares Mendes-Giannini, Ana Marisa eFusco-Almeida
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2016-01-01
coleção:	Frontiers in Microbiology
Assuntos:	Host-Pathogen Interactions Histoplasma capsulatum nucleus alveolar macrophages intracellular arrangement
Acesso em linha:	http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01526/full
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