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Inhibition of intracellular Histoplasma capsulatum replication by murine macrophages that produce human defensin.

Although purified defensins are effective microbicides in vitro, their operation within intact phagocytes has not been established. To address this question, we inserted cDNA encoding human defensin HNP-1 into a pBabe/neo retroviral vector and transduced it into RAW 264.7 cells, a murine macrophage...

詳細記述

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書誌詳細
出版年:Infect Immun
主要な著者: Couto, M A, Liu, L, Lehrer, R I, Ganz, T
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1994
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186521/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8188361/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.6.2375-2378.1994
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