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Assessing the clinical significance of botanical supplementation on human cytochrome P450 3A activity: Comparison of a milk thistle and black cohosh product to rifampin and clarithromycin

Phytochemical-mediated modulation of cytochrome P450 enzymes (CYPs) may underlie many herb-drug interactions. This study’s purpose was to assess the effects of milk thistle and black cohosh supplementation on CYP3A activity and compare them to a clinically recognized inducer, rifampin, and inhibitor...

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Detalhes bibliográficos
Main Authors: Gurley, Bill, Hubbard, Martha A., Williams, D. Keith, Thaden, John, Tong, Yudong, Gentry, W. Brooks, Breen, Philip, Carrier, Danielle J., Cheboyina, Shreekar
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865122/
https://ncbi.nlm.nih.gov/pubmed/16432272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0091270005284854
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