In vivo effects of goldenseal, kava kava, black cohosh, and valerian on human cytochrome P450 1A2, 2D6, 2E1, and 3A4 phenotypes

OBJECTIVES: Phytochemical-mediated modulation of cytochrome P-450 activity may underlie many herb-drug interactions. Single time-point, phenotypic metabolic ratios were used to determine whether long-term supplementation of goldenseal (Hydrastis canadensis), black cohosh (Cimicifuga racemosa), kava...

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Hoofdauteurs: Gurley, Bill J., Gardner, Stephanie F., Hubbard, Martha A., Williams, D. Keith, Gentry, W. Brooks, Khan, Ikhlas A., Shah., Amit
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2005
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1894911/
https://ncbi.nlm.nih.gov/pubmed/15900287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clpt.2005.01.009
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