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Transfection with anti-p65 intrabody suppresses invasion and angiogenesis in glioma cells by blocking NF-κB transcriptional activity

PURPOSE: The strategy of intracellular antibodies to neutralize the function of target proteins has been widely developed for cancer research. This study used an intrabody against p65 subunit to prevent NF-κB transcriptional activity in glioma cells and to inhibit the expression of its target genes...

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Detalhes bibliográficos
Main Authors: Li, Liang, Gondi, Christopher S., Dinh, Dzung H., Olivero, William C., Gujrati, Meena, Rao, Jasti S
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865104/
https://ncbi.nlm.nih.gov/pubmed/17404102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-06-1711
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