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Ovol1 represses its own transcription by competing with transcription activator c-Myb and by recruiting histone deacetylase activity
Ovol1 belongs to a family of evolutionarily conserved zinc finger proteins that act downstream of key developmental signaling pathways such as Wnt and TGF-β/BMP. It plays important roles in epithelial and germ cell development, particularly by repressing c-Myc and Id2 genes and modulating the balanc...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1865076/ https://ncbi.nlm.nih.gov/pubmed/17311813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl1141 |
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