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The 30-kDa C-terminal domain of the RecB protein is critical for the nuclease activity, but not the helicase activity, of the RecBCD enzyme from Escherichia coli

The RecBCD enzyme from Escherichia coli is an ATP-dependent helicase and an ATP-stimulated nuclease. The 3′ → 5′ exonuclease activity on double-stranded DNA is suppressed when the enzyme encounters a recombinational hot spot, called chi (χ). We have prepared a RecB deletion mutant (RecB(1–929)) by u...

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Hlavní autoři: Yu, Misook, Souaya, Jehanne, Julin, Douglas A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC18645/
https://ncbi.nlm.nih.gov/pubmed/9448271
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