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Akt1 governs breast cancer progression in vivo
The serine threonine kinase Akt1 has been implicated in the control of cellular metabolism, survival and growth. Here, disruption of the ubiquitously expressed member of the Akt family of genes, Akt1, in the mouse demonstrates a requirement for Akt1 in ErbB2-induced mammary tumorigenesis. Akt1 defic...
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主要な著者: | , , , , , , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
National Academy of Sciences
2007
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1863437/ https://ncbi.nlm.nih.gov/pubmed/17460049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605874104 |
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