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Saccharomyces Rrm3p, a 5′ to 3′ DNA helicase that promotes replication fork progression through telomeric and subtelomeric DNA
In wild-type Saccharomyces cerevisiae, replication forks slowed during their passage through telomeric C(1–3)A/TG(1–3) tracts. This slowing was greatly exacerbated in the absence of RRM3, shown here to encode a 5′ to 3′ DNA helicase. Rrm3p-dependent fork progression was seen at a modified Chromosome...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC186315/ https://ncbi.nlm.nih.gov/pubmed/12050116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.982902 |
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