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The Amino Terminus of the Saccharomyces cerevisiae DNA Helicase Rrm3p Modulates Protein Function Altering Replication and Checkpoint Activity

The Pif1 family of DNA helicases is conserved from yeast to humans. Although the helicase domains of family members are well conserved, the amino termini of these proteins are not. The Saccharomyces cerevisiae genome encodes two Pif1 family members, Rrm3p and Pif1p, that have very different function...

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Bibliographic Details
Main Authors: Bessler, Jessica B., Zakian, Virginia A.
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448792/
https://ncbi.nlm.nih.gov/pubmed/15579680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.028035
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