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Lipoplex formulation of superior efficacy exhibits high surface activity and fusogenicity, and readily releases DNA

Lipoplexes containing a mixture of cationic phospholipids dioleoylethylphosphatidylcholine (EDOPC) and dilauroylethylphosphatidylcholine (EDLPC) are known to be far more efficient agents in transfection of cultured primary endothelial cells than are lipoplexes containing either lipid alone. The larg...

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Detalhes bibliográficos
Main Authors: Koynova, Rumiana, Tarahovsky, Yury S., Wang, Li, MacDonald, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1861830/
https://ncbi.nlm.nih.gov/pubmed/17156744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2006.10.016
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