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DNA Release from Lipoplexes by Anionic Lipids: Correlation with Lipid Mesomorphism, Interfacial Curvature, and Membrane Fusion

DNA release from lipoplexes is an essential step during lipofection and is probably a result of charge neutralization by cellular anionic lipids. As a model system to test this possibility, fluorescence resonance energy transfer between DNA and lipid covalently labeled with Cy3 and BODIPY, respectiv...

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Detalhes bibliográficos
Main Authors: Tarahovsky, Yury S., Koynova, Rumiana, MacDonald, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304446/
https://ncbi.nlm.nih.gov/pubmed/15298910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.042895
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