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Mitotic Kinesin Inhibitors Induce Mitotic Arrest and Cell Death in Taxol-resistant and -sensitive Cancer Cells*

Taxanes are powerful chemotherapy agents that target the microtubule cytoskeleton, leading to mitotic arrest and cell death; however, their clinical efficacy has been hampered due to the development of drug resistance. Therefore, other proteins involved in spindle assembly are being examined as pote...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Marcus, Adam I., Peters, Ulf, Thomas, Shala L., Garrett, Sarah, Zelnak, Amelia, Kapoor, Tarun M., Giannakakou, Paraskevi
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2005
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1861807/
https://ncbi.nlm.nih.gov/pubmed/15653676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M413471200
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