Φορτώνει......
Rapid induction of apoptosis during Kinesin-5 inhibitor-induced mitotic arrest in HL60 cells
Small molecule inhibitors of Kinesin-5 (K5Is) that arrest cells in mitosis with monopolar spindles are promising anti-cancer drug candidates. Clinical trials of K5Is revealed dose-limiting neutropenia, or loss of neutrophils, for which the molecular mechanism is unclear. We investigated the effects...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2011
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3155259/ https://ncbi.nlm.nih.gov/pubmed/21782324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2011.05.024 |
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