Analysis of telomerase catalytic subunit mutants in vivo and in vitro in Schizosaccharomyces pombe

The chromosome end-replicating enzyme telomerase is composed of a template-containing RNA subunit, a reverse transcriptase (TERT), and additional proteins. The importance of conserved amino acid residues in Trt1p, the TERT of Schizosaccharomyces pombe, was tested. Mutation to alanine of the proposed...

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Detaylı Bibliyografya
Asıl Yazarlar: Haering, Christian H., Nakamura, Toru M., Baumann, Peter, Cech, Thomas R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2000
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC18609/
https://ncbi.nlm.nih.gov/pubmed/10829083
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