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Analysis of telomerase catalytic subunit mutants in vivo and in vitro in Schizosaccharomyces pombe

The chromosome end-replicating enzyme telomerase is composed of a template-containing RNA subunit, a reverse transcriptase (TERT), and additional proteins. The importance of conserved amino acid residues in Trt1p, the TERT of Schizosaccharomyces pombe, was tested. Mutation to alanine of the proposed...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Haering, Christian H., Nakamura, Toru M., Baumann, Peter, Cech, Thomas R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2000
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC18609/
https://ncbi.nlm.nih.gov/pubmed/10829083
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