Analysis of telomerase catalytic subunit mutants in vivo and in vitro in Schizosaccharomyces pombe
The chromosome end-replicating enzyme telomerase is composed of a template-containing RNA subunit, a reverse transcriptase (TERT), and additional proteins. The importance of conserved amino acid residues in Trt1p, the TERT of Schizosaccharomyces pombe, was tested. Mutation to alanine of the proposed...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2000
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18609/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10829083/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.130187397 |
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