Ketoconazole inhibition of testicular secretion of testosterone and displacement of steroid hormones from serum transport proteins.

In vivo perfusion of canine testes with ketoconazole inhibited the stimulation of testosterone production by human chorionic gonadotropin in a dose-dependent manner. Ketoconazole also selectively displaced steroids from serum-binding globulins. Dihydrotestosterone and estradiol binding to sex hormon...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Grosso, D S, Boyden, T W, Pamenter, R W, Johnson, D G, Stevens, D A, Galgiani, J N
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1983
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186023/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6301363/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.23.2.207
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