Pharmacology and toxicity of high-dose ketoconazole.

One hundred sixty patients were entered in two multicenter protocols to receive 400 to 2,000 mg of ketoconazole once daily for nonmeningeal or meningeal coccidiodomycosis. For 24 h after administration of all doses, mean concentrations in serum exceeded MICs for Coccidioides immitis (trough concentr...

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Main Authors: Sugar, A M, Alsip, S G, Galgiani, J N, Graybill, J R, Dismukes, W E, Cloud, G A, Craven, P C, Stevens, D A
Format: Artigo
Jezik:Inglês
Izdano: 1987
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC175818/
https://ncbi.nlm.nih.gov/pubmed/3326525
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