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Pharmacology and toxicity of high-dose ketoconazole.

One hundred sixty patients were entered in two multicenter protocols to receive 400 to 2,000 mg of ketoconazole once daily for nonmeningeal or meningeal coccidiodomycosis. For 24 h after administration of all doses, mean concentrations in serum exceeded MICs for Coccidioides immitis (trough concentr...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Sugar, A M, Alsip, S G, Galgiani, J N, Graybill, J R, Dismukes, W E, Cloud, G A, Craven, P C, Stevens, D A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 1987
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175818/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3326525/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.12.1874
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