Ketoconazole inhibition of testicular secretion of testosterone and displacement of steroid hormones from serum transport proteins.

In vivo perfusion of canine testes with ketoconazole inhibited the stimulation of testosterone production by human chorionic gonadotropin in a dose-dependent manner. Ketoconazole also selectively displaced steroids from serum-binding globulins. Dihydrotestosterone and estradiol binding to sex hormon...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Grosso, D S, Boyden, T W, Pamenter, R W, Johnson, D G, Stevens, D A, Galgiani, J N
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1983
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186023/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6301363/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.23.2.207
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