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Apoptosis in retinal degeneration involves cross-talk between apoptosis-inducing factor (AIF) and caspase-12 and is blocked by calpain inhibitors

Molecular mechanisms underlying apoptosis in retinitis pigmentosa, as in other neurodegenerative diseases, are still elusive, and this fact hampers the development of a cure for this blinding disease. We show that two apoptotic pathways, one from the mitochondrion and one from the endoplasmic reticu...

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מידע ביבליוגרפי
Main Authors: Sanges, Daniela, Comitato, Antonella, Tammaro, Roberta, Marigo, Valeria
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2006
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1859935/
https://ncbi.nlm.nih.gov/pubmed/17088543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606276103
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