A mouse model for the delta F508 allele of cystic fibrosis.
The most common cause of cystic fibrosis is a mutation that deletes phenylalanine 508 in cystic fibrosis transmembrane conductance regulator (CFTR). The delta F508 protein is misprocessed and degraded rather than traveling to the apical membrane. We used a novel strategy to introduce the delta F508...
Enregistré dans:
| Publié dans: | J Clin Invest |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Clinical Investigation
1995
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185844/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7560099/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118253 |
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