Presenilin 1 is linked with γ-secretase activity in the detergent solubilized state

γ-Secretase is a membrane-associated protease that cleaves within the transmembrane region of amyloid precursor protein to generate the C termini of the two Aβ peptide isoforms, Aβ40 and Aβ42. Here we report the detergent solubilization and partial characterization of γ-secretase. The activity of so...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Li, Yue-Ming, Lai, Ming-Tain, Xu, Min, Huang, Qian, DiMuzio-Mower, Jillian, Sardana, Mohinder K., Shi, Xiao-Ping, Yin, Kuo-Chang, Shafer, Jules A., Gardell, Stephen J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The National Academy of Sciences 2000
विषय:
Biological Sciences
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC18571/
https://ncbi.nlm.nih.gov/pubmed/10801983
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