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Relation between viral fitness and immune escape within the hepatitis C virus protease
BACKGROUND: The hepatitis C virus (HCV) mutates within human leucocyte antigen (HLA) class I restricted immunodominant epitopes of the non‐structural (NS) 3/4A protease to escape cytotoxic T lymphocyte (CTL) recognition and promote viral persistence. However, variability is not unlimited, and someti...
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| Hauptverfasser: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BMJ Group
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1856491/ https://ncbi.nlm.nih.gov/pubmed/16105887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2005.072231 |
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