Functional Aspects of Intrahepatic Hepatitis B Virus-specific T Cells Induced by Therapeutic DNA Vaccination

Current therapies for the hepatitis B virus (HBV), a major cause of severe liver disease, suppress viral replication but replication rebounds if therapy is withdrawn. It is widely accepted that immune activation is needed to control replication off-therapy. To specifically activate T cells crossreac...

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Bibliographic Details
Published in:Mol Ther
Main Authors: Brass, Anette, Frelin, Lars, Milich, David R, Sällberg, Matti, Ahlén, Gustaf
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351461/
https://ncbi.nlm.nih.gov/pubmed/25492563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.233
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