Identification of mismatch repair gene mutations in young patients with colorectal cancer and in patients with multiple tumours associated with hereditary non‐polyposis colorectal cancer

BACKGROUND: Patients with early‐onset colorectal cancer (CRC) or those with multiple tumours associated with hereditary non‐polyposis colorectal cancer (HNPCC) raise suspicion of the presence of germline DNA mismatch repair (MMR) gene mutations. AIM: To analyse the value of family history, microsate...

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Detalhes bibliográficos
Main Authors: Niessen, R C, Berends, M J W, Wu, Y, Sijmons, R H, Hollema, H, Ligtenberg, M J L, de Walle, H E K, de Vries, E G E, Karrenbeld, A, Buys, C H C M, van der Zee, A G J, Hofstra, R M W, Kleibeuker, J H
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2006
Assuntos:
Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1856475/
https://ncbi.nlm.nih.gov/pubmed/16636019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2005.090159
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