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Proximal adenomas in hereditary non-polyposis colorectal cancer are prone to rapid malignant transformation

Background: Hereditary non-polyposis colorectal cancer (HNPCC) is thought to arise from adenomas. HNPCC mostly occurs in the proximal colon. We investigated whether this proximal preponderance is due to a proximal preponderance of adenomas or (also) differences in transformation rates from adenomas...

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Detalhes bibliográficos
Main Authors: Rijcken, F E M, Hollema, H, Kleibeuker, J H
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2002 by Gut 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773133/
https://ncbi.nlm.nih.gov/pubmed/11839719
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