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pilQ Missense Mutations Have Diverse Effects on PilQ Multimer Formation, Piliation, and Pilus Function in Neisseria gonorrhoeae

Type IV pili are required for virulence in Neisseria gonorrhoeae, as they are involved in adherence to host epithelium, twitching motility, and DNA transformation. The outer membrane secretin PilQ forms a homododecameric ring through which the pilus is proposed to be secreted. pilQ null mutants are...

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Hlavní autoři: Helm, R. Allen, Barnhart, Michelle M., Seifert, H. Steven
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855849/
https://ncbi.nlm.nih.gov/pubmed/17277065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01833-06
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