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pilQ Missense Mutations Have Diverse Effects on PilQ Multimer Formation, Piliation, and Pilus Function in Neisseria gonorrhoeae

Type IV pili are required for virulence in Neisseria gonorrhoeae, as they are involved in adherence to host epithelium, twitching motility, and DNA transformation. The outer membrane secretin PilQ forms a homododecameric ring through which the pilus is proposed to be secreted. pilQ null mutants are...

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Autores principales: Helm, R. Allen, Barnhart, Michelle M., Seifert, H. Steven
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855849/
https://ncbi.nlm.nih.gov/pubmed/17277065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01833-06
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