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pilQ Missense Mutations Have Diverse Effects on PilQ Multimer Formation, Piliation, and Pilus Function in Neisseria gonorrhoeae

Type IV pili are required for virulence in Neisseria gonorrhoeae, as they are involved in adherence to host epithelium, twitching motility, and DNA transformation. The outer membrane secretin PilQ forms a homododecameric ring through which the pilus is proposed to be secreted. pilQ null mutants are...

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Détails bibliographiques
Auteurs principaux: Helm, R. Allen, Barnhart, Michelle M., Seifert, H. Steven
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855849/
https://ncbi.nlm.nih.gov/pubmed/17277065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01833-06
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