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Role of Homoserine Transacetylase as a New Target for Antifungal Agents
Microbial amino acid biosynthesis is a proven yet underexploited target of antibiotics. The biosynthesis of methionine in particular has been shown to be susceptible to small-molecule inhibition in fungi. The first committed step in Met biosynthesis is the acylation of homoserine (Hse) by the enzyme...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1855549/ https://ncbi.nlm.nih.gov/pubmed/17353245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01400-06 |
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