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Mechanism of Action of Efinaconazole, a Novel Triazole Antifungal Agent
The mechanism of action of efinaconazole, a new triazole antifungal, was investigated with Trichophyton mentagrophytes and Candida albicans. Efinaconazole dose-dependently decreased ergosterol production and accumulated 4,4-dimethylsterols and 4α-methylsterols at concentrations below its MICs. Efina...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3632939/ https://ncbi.nlm.nih.gov/pubmed/23459486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02063-12 |
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