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Acquired Echinocandin Resistance in a Candida krusei Isolate Due to Modification of Glucan Synthase
A Candida krusei strain from a patient with acute myelogenous leukemia that displayed reduced susceptibility to echinocandin drugs contained a heterozygous mutation, T2080K, in FKS1. The resulting Phe655→Cys substitution altered the sensitivity of glucan synthase to echinocandin drugs, consistent wi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1855530/ https://ncbi.nlm.nih.gov/pubmed/17325225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00067-07 |
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