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Pharmacokinetic/Pharmacodynamic Factors Influencing Emergence of Resistance to Linezolid in an In Vitro Model

Emerging resistance threatens the usefulness of linezolid for the treatment of severe infections caused by multidrug-resistant gram-positive bacteria. Optimal pharmacokinetic (PK)/pharmacodynamic (PD) indices have been described for the antimicrobial efficacy of linezolid (area under the concentrati...

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Detalhes bibliográficos
Main Authors: Boak, Lauren M., Li, Jian, Rayner, Craig R., Nation, Roger L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855482/
https://ncbi.nlm.nih.gov/pubmed/17242144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01194-06
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