Activities of Ciprofloxacin and Moxifloxacin against Stenotrophomonas maltophilia and Emergence of Resistant Mutants in an In Vitro Pharmacokinetic-Pharmacodynamic Model

A two-compartment in vitro pharmacokinetic-pharmacodynamic model, with full computer-controlled devices, was used to accurately simulate human plasma pharmacokinetic profiles after multidose oral regimens of ciprofloxacin (750 mg every 12 h) and moxifloxacin (400 mg every 24 h) during 48 h. Pharmaco...

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Detalhes bibliográficos
Main Authors: Ba, Boubakar B., Feghali, Hala, Arpin, Corinne, Saux, Marie-Claude, Quentin, Claudine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2004
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC353051/
https://ncbi.nlm.nih.gov/pubmed/14982788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.3.946-953.2004
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