Inhibition of Notch Signaling Induces Neural Differentiation in Ewing Sarcoma

Cells from Ewing sarcoma exhibit cellular features and express markers, suggesting that the tumor is of neuroectodermal origin. Because Notch signaling regulates the differentiation of neuroectodermal cells during development, we examined the role of Notch signaling in Ewing sarcomas. We found that...

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Bibliografiske detaljer
Main Authors: Baliko, Frank, Bright, Tamara, Poon, Raymond, Cohen, Brenda, Egan, Sean E., Alman, Benjamin A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2007
Fag:
Regular Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854963/
https://ncbi.nlm.nih.gov/pubmed/17456774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060971
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