Inhibition of Notch Signaling Induces Neural Differentiation in Ewing Sarcoma

Cells from Ewing sarcoma exhibit cellular features and express markers, suggesting that the tumor is of neuroectodermal origin. Because Notch signaling regulates the differentiation of neuroectodermal cells during development, we examined the role of Notch signaling in Ewing sarcomas. We found that...

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Main Authors: Baliko, Frank, Bright, Tamara, Poon, Raymond, Cohen, Brenda, Egan, Sean E., Alman, Benjamin A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2007
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854963/
https://ncbi.nlm.nih.gov/pubmed/17456774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060971
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