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Maternal Nanos represses hid/skl-dependent apoptosis to maintain the germ line in Drosophila embryos

Nanos (Nos) is an evolutionarily conserved protein essential for the survival of primordial germ cells. In Drosophila, maternal Nos partitions into pole cells and suppresses apoptosis to permit proper germ-line development. However, how this critical event is regulated by Nos has remained elusive. H...

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Bibliografske podrobnosti
Main Authors: Sato, Kimihiro, Hayashi, Yoshiki, Ninomiya, Yuichi, Shigenobu, Shuji, Arita, Kayo, Mukai, Masanori, Kobayashi, Satoru
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854842/
https://ncbi.nlm.nih.gov/pubmed/17449640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610052104
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