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Maintaining Sufficient Nanos Is a Critical Function for Polar Granule Component in the Specification of Primordial Germ Cells

Primordial germ cells (PGC) are the precursors of germline stem cells. In Drosophila, PGC specification is thought to require transcriptional quiescence and three genes, polar granule component (pgc), nanos (nos), and germ cell less (gcl) function to downregulate Pol II transcription. While it is no...

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Detalhes bibliográficos
Main Authors: Deshpande, Girish, Spady, Emma, Goodhouse, Joe, Schedl, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484670/
https://ncbi.nlm.nih.gov/pubmed/23173091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.112.004192
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