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Maintaining Sufficient Nanos Is a Critical Function for Polar Granule Component in the Specification of Primordial Germ Cells

Primordial germ cells (PGC) are the precursors of germline stem cells. In Drosophila, PGC specification is thought to require transcriptional quiescence and three genes, polar granule component (pgc), nanos (nos), and germ cell less (gcl) function to downregulate Pol II transcription. While it is no...

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Bibliografiske detaljer
Main Authors: Deshpande, Girish, Spady, Emma, Goodhouse, Joe, Schedl, Paul
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484670/
https://ncbi.nlm.nih.gov/pubmed/23173091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.112.004192
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