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Maternal Nanos represses hid/skl-dependent apoptosis to maintain the germ line in Drosophila embryos

Nanos (Nos) is an evolutionarily conserved protein essential for the survival of primordial germ cells. In Drosophila, maternal Nos partitions into pole cells and suppresses apoptosis to permit proper germ-line development. However, how this critical event is regulated by Nos has remained elusive. H...

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Main Authors: Sato, Kimihiro, Hayashi, Yoshiki, Ninomiya, Yuichi, Shigenobu, Shuji, Arita, Kayo, Mukai, Masanori, Kobayashi, Satoru
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854842/
https://ncbi.nlm.nih.gov/pubmed/17449640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610052104
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