Human NANOS1 Represses Apoptosis by Downregulating Pro-Apoptotic Genes in the Male Germ Cell Line

While two mouse NANOS paralogues, NANOS2 and NANOS3, are crucial for maintenance of germ cells by suppression of apoptosis, the mouse NANOS1 paralogue does not seem to regulate these processes. Previously, we described a human NANOS1 p.[(Pro34Thr);(Ser83del)] mutation associated with the absence of...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Janecki, Damian M., Ilaslan, Erkut, Smialek, Maciej J., Sajek, Marcin P., Kotecki, Maciej, Ginter-Matuszewska, Barbara, Krainski, Patryk, Jaruzelska, Jadwiga, Kusz-Zamelczyk, Kamila
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7215683/
https://ncbi.nlm.nih.gov/pubmed/32344590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21083009
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