SPIN1 is a proto-oncogene and SPIN3 is a tumor suppressor in human seminoma

SPIN1 is necessary for normal meiotic progression in mammals. It is overexpressed in human ovarian cancers and some cancer cell lines. Here, we examined the functional significance and regulation of SPIN1 and SPIN3 in the TCam-2 human seminoma cell line. We found that while SPIN1 overexpression redu...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Janecki, Damian Mikolaj, Sajek, Marcin, Smialek, Maciej Jerzy, Kotecki, Maciej, Ginter-Matuszewska, Barbara, Kuczynska, Bogna, Spik, Anna, Kolanowski, Tomasz, Kitazawa, Riko, Kurpisz, Maciej, Jaruzelska, Jadwiga
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2018
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126697/
https://ncbi.nlm.nih.gov/pubmed/30197756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25977
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