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SPIN1 is a proto-oncogene and SPIN3 is a tumor suppressor in human seminoma

SPIN1 is necessary for normal meiotic progression in mammals. It is overexpressed in human ovarian cancers and some cancer cell lines. Here, we examined the functional significance and regulation of SPIN1 and SPIN3 in the TCam-2 human seminoma cell line. We found that while SPIN1 overexpression redu...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Janecki, Damian Mikolaj, Sajek, Marcin, Smialek, Maciej Jerzy, Kotecki, Maciej, Ginter-Matuszewska, Barbara, Kuczynska, Bogna, Spik, Anna, Kolanowski, Tomasz, Kitazawa, Riko, Kurpisz, Maciej, Jaruzelska, Jadwiga
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126697/
https://ncbi.nlm.nih.gov/pubmed/30197756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25977
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