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High Affinity of Carbamate Analogues of Morphinan atOpioid Receptors
A series of carbamate analogues were synthesized from levorphanol (1a), cyclorphan (2a) or butorphan (3a) and evaluated in vitro by their binding affinity at μ, δ and κ opioid receptors. Functional activities of these compounds were measured in the [(35)S]GTPγS binding assay. Phenyl carbamate deriva...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1853345/ https://ncbi.nlm.nih.gov/pubmed/17276685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.01.03 |
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