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Oligodendrocyte Apoptosis and Primary Demyelination Induced by Local TNF/p55TNF Receptor Signaling in the Central Nervous System of Transgenic Mice : Models for Multiple Sclerosis with Primary Oligodendrogliopathy

The scientific dogma that multiple sclerosis (MS) is a disease caused by a single pathogenic mechanism has been challenged recently by the heterogeneity observed in MS lesions and the realization that not all patterns of demyelination can be modeled by autoimmune-triggered mechanisms. To evaluate th...

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Autors principals: Akassoglou, Katerina, Bauer, Jan, Kassiotis, George, Pasparakis, Manolis, Lassmann, Hans, Kollias, George, Probert, Lesley
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853008/
https://ncbi.nlm.nih.gov/pubmed/9736029
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