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Uncoupling the Proinflammatory from the Immunosuppressive Properties of Tumor Necrosis Factor (Tnf) at the P55 TNF Receptor Level: Implications for Pathogenesis and Therapy of Autoimmune Demyelination

Multiple sclerosis (MS) is a disabling inflammatory demyelinating disease of the central nervous system, considered to result from self-reactivity to myelin antigens. Tumor necrosis factor (TNF) and the p55 TNF receptor (TNFR) have been strongly implicated in MS pathogenesis. We reveal in this study...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kassiotis, George, Kollias, George
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195909/
https://ncbi.nlm.nih.gov/pubmed/11181695
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