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Exclusive tumor necrosis factor (TNF) signaling by the p75TNF receptor triggers inflammatory ischemia in the CNS of transgenic mice

Tumor necrosis factor (TNF) is up-regulated in a variety of central nervous system (CNS) diseases with diverse etiology and pathologic manifestation. TNF mediates multiple biological activities through two membrane receptors, the p55 and p75 TNF receptors (TNFRs). We have shown previously that human...

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Библиографические подробности
Главные авторы: Akassoglou, Katerina, Douni, Eleni, Bauer, Jan, Lassmann, Hans, Kollias, George, Probert, Lesley
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 2003
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC141061/
https://ncbi.nlm.nih.gov/pubmed/12522266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0236046100
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