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Exclusive tumor necrosis factor (TNF) signaling by the p75TNF receptor triggers inflammatory ischemia in the CNS of transgenic mice

Tumor necrosis factor (TNF) is up-regulated in a variety of central nervous system (CNS) diseases with diverse etiology and pathologic manifestation. TNF mediates multiple biological activities through two membrane receptors, the p55 and p75 TNF receptors (TNFRs). We have shown previously that human...

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Detalhes bibliográficos
Main Authors: Akassoglou, Katerina, Douni, Eleni, Bauer, Jan, Lassmann, Hans, Kollias, George, Probert, Lesley
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC141061/
https://ncbi.nlm.nih.gov/pubmed/12522266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0236046100
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