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Role of p27(Kip1) and Cyclin-Dependent Kinase 2 in the Proliferation of Non-Small Cell Lung Cancer
The cell cycle is governed by a family of cyclin-dependent kinases (Cdks). Cdk2 forms a functional complex with cyclin E and plays a pivotal role in the regulation of G1/S transition. Cdk2 activity is negatively regulated by interactions with inhibitors. p27(Kip1), one of the most potent inhibitors...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Investigative Pathology
1998
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852977/ https://ncbi.nlm.nih.gov/pubmed/9708810 |
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