Mantle Cell Lymphomas Lack Expression of p27(kip1), a Cyclin-Dependent Kinase Inhibitor

p27(Kip1) is a cyclin-dependent kinase inhibitor that regulates the decision to enter S phase or withdraw from the cell cycle. In resting cells, the level of p27(Kip1) provides an inhibitory threshold above which G1 cyclin D/E/cyclin-dependent kinases accumulate before activation; however, in cyclin...

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Bibliographic Details
Main Authors: Quintanilla-Martinez, Leticia, Thieblemont, Catherine, Fend, Falko, Kumar, Shimareet, Pinyol, Magda, Campo, Elias, Jaffe, Elaine S., Raffeld, Mark
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 1998
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852938/
https://ncbi.nlm.nih.gov/pubmed/9665478
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